Clinical Effects of TRH Analog (DN-1417) on Lennox Syndrome
نویسندگان
چکیده
منابع مشابه
Effects of TRH and an analog, DN-1417 on the activities of single neurons in the nucleus accumbens, cerebral cortex and caudate-putamen of rats.
The actions of TRH and its analog, y butyrolactone y -carbonyl histidyl prolinamide citrate (DN-1417) on the unit activities of the cerebral cortex, caudate -putamen and nucleus accumbens were examined using a microelec trophoretic technique in anesthetized rats. Over 80% of the neurons examined in the nucleus accumbens responded to TRH and DN -1417. The effects were mainly inhibitory, but exci...
متن کاملA thyrotropin releasing hormone analog, DN-1417, increases endogenous dopamine release from slices of rat striatum and nucleus accumbens.
Besides its hormonal effects, thyrotro pin releasing hormone (TRH) induces se veral behavioral changes in rats. Marked increases in locomotor activity occur after administration of TRH and its analogs. This effect was hypothesized to be due to a stimulation of mesolimbic dopaminergic neurons (Miyamoto and Nagawa, 1977; Heal and Green, 1979). TRH has no effect on the reuptake of monoamines (Tuom...
متن کاملLennox-Gastaut syndrome
بيصت ةديدش ةيعرص ةمزلاتم يه وتساج سكونيل ةمزلاتم ةرركتمو ةعونتم ةيبصع تاجنشت ةباصإب زيمتتو لافطلأا ةئيطب ةيئابرهك تانحشو روهدتم ينهذ رخأتب ةبوحصم نادقفب ةبوحصلما ةيبصعلا تاجنشتلا لثتمو .غامدلا طيطختب ةيعون روهدتو ةيدسلجا تاباصلإاب ةروطخ طوقسلاو ةكرلحا ةلوهسب بيجتست لا تاجنشتلا هذه نأ ملعلا عم .ةيمويلا ةايلحا .ضرغلا اذهل ديامانيفورلا راقع ريوطت تم اًيلاحو يئاودلا جلاعلل ضعب مادختسا نكميف يئاودلا ...
متن کاملLennox-Gastaut syndrome (LGS)
Key-words Disease name and synonymes Excluded diseases Diagnostic criteria / definition Differential diagnosis Frequency Clinical description Management including treatment Etiology Diagnostic methods Genetic counselling Unresolved questions References Abstract Lennox-Gastaut syndrome (LGS) belongs to the group of severe childhood epileptic encephalopathies. This disorder is defined as a crypto...
متن کاملLennox-Gastaut syndrome
By Mary C Spiciarich MD (Dr. Spiciarich of Albert Einstein College of Medicine and Montefiore Medical Center has no relevant financial relationships to disclose.) Solomon L Moshe MD (Dr. Moshe of Albert Einstein College of Medicine received honorariums from Eisai for speaking engagements and from UCB as a member of the data and safety monitoring board.) Originally released July 26, 1994; last u...
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ژورنال
عنوان ژورنال: Journal of the Japan Epilepsy Society
سال: 1983
ISSN: 0912-0890,1347-5509
DOI: 10.3805/jjes.1.31